BARNSLEY RUFC women lost 63-17 at leaders Cheltenham Tigers in Championship One North.
The Shaw Laners are sixth, ten points clear of the bottom two.
They now have two games left this season, starting at West Park Leeds on Saturday.
Barnsley men host leaders Old Otliensians in Yorkshire Division Three on Saturday after a two-week break.
The Shaw Laners are third-bottom and six points clear of the bottom two, with two games left. They could secure their safety this weekend depending on their result and others.
Wath are due to visit second-bottom Leodiensian in their penultimate Yorkshire Division One game of the season.
Dearne Valley are due to host Wortley in an all-Barnsley clash in Yorkshire Division Four on Saturday.
Dearne are champions and have two games to play while second-bottom Wortley will finish their league season with this game.